Therapeuticindexdatabase

Aratiothatcomparesthebloodconcentrationatwhichadrugbecomestoxicandtheconcentrationatwhichthedrugiseffective.Thelargerthetherapeutic ...,InDrugBank'sdatabase,thedecisiontoconsideradruganarrowtherapeuticindexdrugisbasedonthefollowing:Professionalconsensus(eg.FDA/EMA/DPDlabel ...,Narrowtherapeuticindex(NTI)drugsaredefinedasthosedrugswheresmalldifferencesindoseorbloodconcentrationmayleadtodoseandb...

參考資訊如下
Therapeutic Index (TI)

A ratio that compares the blood concentration at which a drug becomes toxic and the concentration at which the drug is effective. The larger the therapeutic ...

Narrow Therapeutic Index Drug

In DrugBank's database, the decision to consider a drug a narrow therapeutic index drug is based on the following: Professional consensus (eg. FDA/EMA/DPD label ...

Narrow Therapeutic Index Drugs

Narrow therapeutic index (NTI) drugs are defined as those drugs where small differences in dose or blood concentration may lead to dose and blood concentration ...

Narrow Therapeutic Index drugs

由 S Habet 著作 · 2021 · 被引用 32 次 — Historically, the identification of drugs with the Narrow Therapeutic Index (NTI) has been empirically based on the clinical practice.

Drugs with narrow therapeutic index as indicators in the ...

由 HS Blix 著作 · 2010 · 被引用 1 次 — ABSTRACT*. Drugs with narrow therapeutic index (NTI-drugs) are drugs with small differences between therapeutic and toxic doses. The pattern of drug-related.

Understanding generic narrow therapeutic index drugs.

2022年11月1日 — Narrow therapeutic index (NTI) drugs are drugs where small differences in dose or blood concentration may lead to serious therapeutic failures ...

Narrow Therapeutic Index Drugs

2017年5月9日 — Narrow therapeutic index drugs are drugs where small differences in dose or blood concentration may lead to serious therapeutic failures and/or ...

Narrow therapeutic index drugs

由 J Tamargo 著作 · 2015 · 被引用 286 次 — The therapeutic index (TI; also known as therapeutic ratio) is a ratio ... database of 236 patients with supraventricular arrhythmias treated in the ...